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The recommended daily dose is 200mg. For patients with narcolepsy and OSA/HA, Modavigil (Modafinil) should be taken as single dose in the morning.

In patients with obstructive sleep apnea/hypopnoea syndrome, modafinil may be added a an adjunct therapy along with the primary disease-modifying interventions like continuous positive Airway pressure (CPAP).

Doses up to 400mg per day, given as a single dose, have ben well tolerated, but there is no consistent evidence that this dose confers additional benefit beyond that of 200mg dose.

Moderate to Severe Chronic Shift Work sleep Disorder. The recommended daily dose is 200mg which should be taken as a single dose approximately 1 hour prior to the start of the work shift.

When we need increased focus during a typical “9-5” workday, then a 100mg Modafinil dosage is probably our ideal starting point.

This seems in line with previously published studies, where 100mg of Modafinil was sufficient for most patients to notice significant differences in cognitive functioning [10].

Due to Modafinil's half-life of 12-15 hours [11], we notice that the boost in cognitive enhancement starts to wear off around 7-8 hours after taking 100mg.

A few team members do prefer splitting up their daily Modafinil dosage of 100mg into two separate doses – 50mg at 7-8 am, and the remaining 50mg at 12-1 pm.

If you take this dosage of Modafinil and don't notice improved focus, keep reading.

This is the standard dose taken by most smart drug users who are seriously using Modafinil to become more energetic and focused for the majority of the working day.

As mentioned before, it is also the most “well-researched” dosage of Modafinil and it is officially recommended in Modafinil's product monograph for patients who are prescribed the drug

At 200mg of Modafinil, we find that most users feel all the desired cognitive effects with little to no side effects.

We find that most Modafinil users in fact do well with this dose at 1-3 days per week. There doesn’t seem to be much clinical evidence to suggest more than 200mg of Modafinil adds additional benefits, or that splitting your Modafinil dosage into two 100mg doses makes any real difference.